COMPOSITION OF SURFACE-ACTIVE MATERIAL ISOLATED FROM BEEF LUNG

Surface-active Material in Fetal Lung Fluid Concentrated by Foaming.

A fluid has been demonstrated to flow from the trachea of fetal lambs1,2). By studies with the modified Wilhelmy balance the fluid has been found to have a very low surface tension when the surface area is compressed to 20% of its maximal size3). These findings are of particular interest since the fluid originates from the lungs and is aspirated with initial aeration. It is likely that the surf...

Surface active materials from dog lung. II. Composition and physiological correlations.

KING, RICHARD J., AND JOHN A. CLEMENTS. Surface actiue materials from dog lung. 11. Composition and physiological correlations. Am. J. Physiol. 223(3) : 715726. 1972.-We studied the chemical composition and physical properties of the four surface active materials obtained from dog lung. All were composed of lipid and protein and contained less than 2y0 hexose and hexosamine. The four fractions ...

Surfactant protein composition of lamellar bodies isolated from rat lung.

Lamellar bodies isolated from rat lung contain all three classes of surfactant proteins, SP-A, SP-B and SP-C, as determined by immunoblot analysis. The amounts of the surfactant proteins present in lamellar bodies, determined by sandwich e.l.i.s.a. (SP-A) and fluorescamine assay (SP-B and SP-C) show that these organelles are highly enriched in the hydrophobic surfactant proteins SP-B and SP-C.

Chronic Hyperglycemia Reduces Surface Active Material

serum glucose levels (18±2 mg/dl, P <0.001) and serum insulin levels (12±3 IAU/ml, P < 0.001) in six chronically catheterized control fetuses of the same gestational ages. Glucose infusion to the fetuses did not alter maternal serum glucose (60±3 mg/dl) or serum insulin levels (35±5 MAU/ml). Arterial blood gases (pH 7.34±0.01, Po2 24.3±0.5 mmHg, Pco2 41.5±0.9 mmHg), oxygen saturation (73±2%), h...

Phospholipid metabolism in lung adenomas: a model of surface active material synthesis.